ABSTRACT
Objective To provide data evidence for brucellosis prevention by a retrospective analysis of brucellosis epidemiologic feature in Ji'nan Infectious Disease Hospital from 2010-2014.Method The brucellosis patients with confinned diagnosis from 2010 to 2014 admitted to Ji'nan Infectious Disease Hospital were included in this study,and their epidemic data were statistically analyzed,including time,age and occupation distributions.Results There were 1 010 brucellosis patients in total in Ji'nan Infectious Disease Hospital from 2010 to 2014,and 12 cases,69 cases,134 cases,274 cases and 521 cases,respectively,in each year,which showed rapid rising trend.There were two peak times,the first was from April to August,the incidence was 9.1％ (92/1 010),12.2％(123/1010),13.4％ (135/1010),11.1％ (112/1010) and 10.7％ (108/1010),respectively,in each month;the second was January,the incidence was 9.4％ (95/1010).The diagnosed rate within 1 week of onset only accounted for 13.4％ (135/1010),and 72.4％ (731/1010) patients were diagnosed for more than two weeks after the onset.The male incidence of brucellosis was higher than the female,and the sex ratio was 2.36:1.00.In terms of age distribution,40-49 and 50-59 were both peak ages,with incidence of 29.3％ (296/1 010) and 25.0％ (252/1010),respectively.The professional was given priority to farmers and herdsmen (85.6％,865/1 010),and 96.4％ (974/1010)of the patients had a clear exposure history,mainly related to sheep,cattle,pigs and other livestock,also related to pets and milk.Conclusions The brucellosis patients that received in Ji'nan Infectious Disease Hospital are increased significantly in the recent 5 years,and their transmission is closely associated with livestock breeding and processing.Most patients have failed timely diagnosis in the early days,which should catch enough of our attention.
ABSTRACT
Objective To explore the relationship between metabolic syndrome (MS) and prostate volume. Methods One thousand and ninety-eight males aged 36-90 years were divided into two groups according to the definition of MS by CDS in 2004 : MS group and control group. The blood pressure, body weight and height were measured, and the body mass index (BMI) was calculated. Biochemical assays including fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and prostate specific antigen (PSA) were performed. Prostate volume was measured by abdominal ultrasound. Results (1) The BMI, systolic blood pressure, diastolic blood pressure, fasting plasma glucose, serum triglyceride, total cholesterol, prostate volume and PSA level were higher, while HDL-C level was lower in MS group than in control group (all P<0.05). (2)Compared with control group, the prostate volume was enlarged in MS group [(37.8±21.3)ml vs. (31.0±11.1)ml, P<0.01]. (3)The prostate volume was positively correlated with PSA level (r= 0. 350, P< 0. 01), age (r = 0. 429, P<0.01), BMI (r=0.145,P<0.01) and systolic blood pressure (r=0.133, P<0.05), and was negatively correlated with diastolic blood pressure (r= -0. 193,P<0. 01). ConclusionsMetabolic syndrome is related to the enlargement of prostate volume.